It’s possible to administer kambo relatively safely, to make the most of its healing benefits. At a very basic level, your facilitator must ask about your medical history, and be aware of any health conditions that could make kambo especially dangerous for you. It is even used traditionally to end pregnancies – and it is not a pleasant process.
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Native to Mexico and the Southwestern US, peyote has long been a focus of Native American and pre-Colombian ceremonial traditions. Its name derives from the Nahuatl term peyotl and it remains legal for ceremonial use in the US under the American Indian Religious Freedom Act. Today, it’s also used in other contexts elsewhere, including in meditation and psychotherapy. It also holds the reputation of being the first psychedelic to come to mainstream Western attention—for better or worse. Due to overharvesting and peyote’s slow-growing nature, the cactus is now an endangered species. Aerodynamically, it’s considerably harder to overdose yourself with self-administered hapé via a kuripe. However, if you have a regular practice of consuming hapé on your own, it’s good to be mindful that it doesn’t turn into an addiction or personal vice.
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In fact, this may be one of its traditional uses; the Tarahumara Indians are said to consume small amounts of the cactus to combat hunger and fatigue while hunting. In general, though, and certainly to avoid nausea, it may be preferable to microdose pure mescaline . For more information, check out our Essential Guide to Microdosing Mescaline. Peyote is legal to grow in many countries even where mescaline is illegal, but this doesn’t include the United States . In many countries, you can buy peyote seeds and living buttons to grow at home. Always check your local laws before cultivating peyote and be aware that, while it’s a relatively low-maintenance cactus to grow, it may take several years to establish a decent-sized garden.
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According to the Global Drug Survey in 2014, mescaline and peyote were among the top 20 drugs used in the past month in Mexico, but nowhere else in the world. Peyote was taken by 6.4% and mescaline by 4.4% of the 643 Mexican survey respondents. Otherwise, both mescaline and peyote are strictly controlled as Schedule I substances. Other mescaline-containing cacti , such as San Pedro, are legal only for ornamental purposes.
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That said, we can trace the popularity of mescaline over time by looking at its appearance in publications and Google searches. Osmond had been investigating mescaline’s molecular similarity to adrenaline as well as its potential for treating mental illness and alcohol dependency. He supplied it to Huxley in 1953, who wrote The Doors of Perception about his mescaline trip the following year.
In 1955, he administered mescaline to British Member of Parliament Christopher Mayhew as part of a BBC documentary. Unfortunately, while Mayhew described the effects in glowing, even mystical terms, the footage was never broadcast. Mescaline is also illegal in the UK and Canada, as well as many European countries. However, peyote and other mescaline-containing cacti are generally legal to grow for ornamental purposes. The same is true in some Australian states, including Victoria and New South Wales, but not in Western Australia, Queensland, and the Northern Territory, where even San Pedro is illegal.